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ea0037ep596 | Obesity and cardiovascular endocrinology | ECE2015

Increased expression of ATP-binding cassette transporter A1 by cilostazol may be a possible mechanism for its protective effect against hepatic steatosis

Cha Bong-Soo , Park Tae Sun , Jeon Byung Hun , Lee Yong-Ho , Yun Mi Ra , Lee Byung Wan , Kang Eun Seok , Lee Hyun Chul

Objective: Cilostazol, a selective inhibitor of phosphodiesterase 3, which has been widely used in patients with atherosclerotic diseases, is known to have additional beneficial effects on dyslipidemia. ATP-binding cassette transporter A1 (ABCA1) plays a critical role in the regulation of intracellular cholesterol levels in hepatocytes. We aimed to investigate the effect of Cilostazol on hepatic steatosis and its underlying mechanism related to ABCA1.Met...

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ePoster

ea0035p189 | Cardiovascular Endocrinology & Lipid Metabolism | ECE2014

Serum cholesterol concentration and prevalence, awareness, treatment, and control of high LDL cholesterol in the Korea National Health and Nutrition Examination Surveys 2008–2010

Lee Yong-ho , Lee Byung-Wan , Kang Eun Seok , Lee Hyun Chul , Baik Sei Hyun , Kim Dong-Sun , Cha Bong Soo

Introduction: The mortality rate from cardiovascular disease (CVD) among young adults has declined less than that in the older population, raising concerns about the increasing prevalence of obesity-related conditions including hypercholesterolemia in the younger population. We investigated the age-standardized mean levels of serum cholesterols and the prevalence, awareness, treatment and control rates of hyper-LDL-cholesterolemia based on age.Methods: N...

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Endocrine Abstracts

Increased expression of ATP-binding cassette transporter A1 by cilostazol may be a possible mechanism for its protective effect against hepatic steatosis

Serum cholesterol concentration and prevalence, awareness, treatment, and control of high LDL cholesterol in the Korea National Health and Nutrition Examination Surveys 2008–2010

BiosciAbstracts